Rivaroxaban Intermediate CAS 446292-07-5 Purity ≥98.0% (HPLC) Factory

Short Description:

Chemical Name: 2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione

CAS: 446292-07-5

Appearance: White Powder

Purity: ≥98.0% (HPLC)

Intermediate of Rivaroxaban (CAS: 366789-02-8) in the treatment of Venous Thromboembolism (VTE) 

Contact: Dr. Alvin Huang 

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com  


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Description:

Chemical Properties:

Chemical Name 2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione
Synonyms Rivaroxaban Intermediate; (S)-2-(2-hydroxy-3-(4-(3-oxomorpholino)phenylamino)propyl)isoindoline-1,3-dione
CAS Number 446292-07-5
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C21H21N3O5
Molecular Weight 395.41
Melting Point 210.0℃~215.0℃
Density 1.421g/cm3
Storage Condition Under Inert Gas (Nitrogen or Argon) at 2~8℃
COA & MSDS Available
Place of Origin  Shanghai, China
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White Powder
Purity / Analysis Method ≥98.0% (HPLC)
Melting Point 210.0℃~215.0℃
Any Individual Impurity ≤1.00%
Loss on Drying ≤0.50%
Residue on Ignition ≤0.10%
Test Standard Enterprise Standard
Usage Rivaroxaban (CAS: 366789-02-8) Intermediate 

Rivaroxaban Intermediates CAS 446292-07-5 Synthesis Route

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement 

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

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Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione (CAS: 446292-07-5) with high quality. It is an intermediate typically in the synthesis of Rivaroxaban (CAS: 366789-02-8). Rivaroxaban is a pure (S)-enantiomer. Rivaroxaban (BAY 59-7939) is an oral, direct factor Xa inhibitor in clinical development for the prevention and treatment of venous thromboembolism (VTE). Rivaroxaban is an antithrombotic drug and was developed in a collaboration between the German Bayer Pharmaceuticals and American Johnson company.

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